Reader’s Question

I Can’t seem to find much information on Remeron and its side effects. I understand with this drug that weight gain is the norm. Is it possible that this drug could have the opposite effect where one loses their appetite and does not eat? Are there any studies that would indicate this as a possibility? This seems to be my issue, and if there is this may be an answer to why I am not eating and continue to lose weight. I am not a teenager with an eating disorder. Any direction or help would be welcomed at this time.

Our Clinical Psychologist’s Reply

Remeron typically has weight gain as a side effect. Major Depression typically has weight loss as a symptom, almost to the point of NO appetite or anorexia.

Based on your description, I think your depression is stronger than your current antidepressant medication. If your Remeron is prescribed by a nonpsychiatrist (typically family MD or OB/GYN), the dose may be too low. If this is true, you will continue to have significant signs of depression including sadness, poor concentration, crying spells, sleep problems, etc. In an odd situation, the use of low-dose Remeron may just make you “calmly depressed”.

It’s very appropriate to be concerned about the continued weight loss despite the medication. I would bring this to the attention of your physician. If your physician is not a psychiatrist, I would recommend consulting a psychiatrist if possible. The current dose of Remeron may be helping you sleep but not improving your depression symptoms. You may need an additional medication or a change in dosage.